| ASHTABULA ST. JOHN SCHOOL Seed: 12 3 |
| Date: 10/19/2021 Time: 4:30 PM |
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25-21, 25-23, 25-21
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| SOUTHINGTON CHALKER Seed: 22 0 |
| WELLSVILLE Seed: 1 3 |
| Date: 10/19/2021 Time: 6:00 PM |
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25-1, 25-5, 25-5
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| Ygstwn. Academy for Urban Scholars Seed: 27 0 |
| LOWELLVILLE Seed: 14 3 |
| Date: 10/19/2021 Time: 7:30 PM |
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26-24, 25-12, 25-11
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| WINDHAM Seed: 18 0 |
| COLUMBIANA Seed: 5 |
| NO CONTEST |
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| WARREN LORDSTOWN Seed: 24 |
| KINSMAN BADGER Seed: 11 3 |
| Date: 10/20/2021 Time: 6:00 PM |
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25-12, 25-10, 25-18
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| LEETONIA Seed: 26 0 |
| SALINEVILLE SOUTHERN Seed: 6 3 |
| Date: 10/20/2021 Time: 7:30 PM |
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25-15, 25-10, 25-11
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| NEW MIDDLETOWN SPRINGFIELD Seed: 20 0 |
| LISBON DAVID ANDERSON Seed: 21 1 |
| Date: 10/21/2021 Time: 6:00 PM |
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21-25, 27-25, 25-15, 25-17
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| ASHTABULA ST. JOHN SCHOOL Seed: 12 3 |
| WELLSVILLE Seed: 1 3 |
| Date: 10/21/2021 Time: 7:30 PM |
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25-10, 25-13, 25-11
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| LOWELLVILLE Seed: 14 0 |
| NORTH JACKSON JACKSON-MILTON Seed: 9 3 |
| Date: 10/23/2021 Time: 6:00 PM |
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25-15, 27-25, 18-25, 25-18
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| COLUMBIANA Seed: 5 1 |
| KINSMAN BADGER Seed: 11 0 |
| Date: 10/23/2021 Time: 7:30 PM |
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25-15, 25-17, 25-13
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| SALINEVILLE SOUTHERN Seed: 6 3 |
| ASHTABULA ST. JOHN SCHOOL Seed: 12 0 |
| Date: 10/27/2021 Time: 6:00 PM |
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25-15, 25-11, 25-11
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| WELLSVILLE Seed: 1 3 |
| NORTH JACKSON JACKSON-MILTON Seed: 9 3 |
| Date: 10/27/2021 Time: 7:30 PM |
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25-21, 25-18, 25-11
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| SALINEVILLE SOUTHERN Seed: 6 0 |
| WELLSVILLE Seed: 1 3 |
| Date: 10/30/2021 Time: 1:00 PM |
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25-23, 25-18, 25-19
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| NORTH JACKSON JACKSON-MILTON Seed: 9 0 |
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