| CASSTOWN MIAMI EAST Seed: 4 3 |
| Date: 10/18/2021 Time: 5:00 PM |
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25-22, 25-14, 25-23
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| MIDDLETOWN MADISON Seed: 11 0 |
| ANNA Seed: 10 1 |
| Date: 10/18/2021 Time: 6:30 PM |
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25-22, 25-18, 21-25, 25-23
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| CAMDEN PREBLE SHAWNEE Seed: 5 3 |
| LEWISTOWN INDIAN LAKE Seed: 8 3 |
| Date: 10/18/2021 Time: 8:00 PM |
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25-16, 25-16, 25-20
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| ARCANUM Seed: 7 0 |
| CIN. CLARK MONTESSORI Seed: 12 0 |
| Date: 10/19/2021 Time: 6:00 PM |
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25-22, 25-17, 25-16
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| NORWOOD Seed: 14 3 |
| CIN. COUNTRY DAY Seed: 9 3 |
| Date: 10/19/2021 Time: 7:30 PM |
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25-15, 25-14, 25-15
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| CIN. DEER PARK Seed: 15 0 |
| WEST ALEXANDRIA TWIN VALLEY SOUTH Seed: 12 0 |
| Date: 10/23/2021 Time: 11:00 AM |
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25-11, 25-5, 25-5
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| CASSTOWN MIAMI EAST Seed: 4 3 |
| CAMDEN PREBLE SHAWNEE Seed: 5 3 |
| Date: 10/23/2021 Time: 12:30 PM |
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25-23, 25-18, 25-19
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| LEWISTOWN INDIAN LAKE Seed: 8 0 |
| CIN. ARCHBISHOP MCNICHOLAS Seed: 3 3 |
| Date: 10/21/2021 Time: 6:00 PM |
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25-11, 25-12, 25-10
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| NORWOOD Seed: 14 0 |
| BLANCHESTER Seed: 7 1 |
| Date: 10/21/2021 Time: 7:30 PM |
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25-21, 22-25, 25-23, 25-15
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| CIN. COUNTRY DAY Seed: 9 3 |
| CASSTOWN MIAMI EAST Seed: 4 1 |
| Date: 10/26/2021 Time: 6:00 PM |
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18-25, 28-26, 25-20, 25-16
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| CAMDEN PREBLE SHAWNEE Seed: 5 3 |
| CIN. ARCHBISHOP MCNICHOLAS Seed: 3 3 |
| Date: 10/26/2021 Time: 6:00 PM |
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25-16, 23-25, 25-11, 25-19
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| CIN. COUNTRY DAY Seed: 9 1 |
| CAMDEN PREBLE SHAWNEE Seed: 5 0 |
| Date: 10/30/2021 Time: 2:00 PM |
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25-15, 25-17, 25-10
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| CIN. ARCHBISHOP MCNICHOLAS Seed: 3 3 |
| CIN. ARCHBISHOP MCNICHOLAS |
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